Columbia University Medical Center
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell
Clinic of the Future: Aiming for Faster Depression Relief
June 25, 2013

 Researchers at Columbia University have used positron emission tomography (PET) scans to predict which patients will get better with antidepressant medication. In one small study published in 2009 in Psychiatry Research of 33 depressed patients, those who responded to drugs had lower activity levels in the midbrain and the rostral anterior cingulate, areas that contain receptors for the neurotransmitter serotonin. The test was able to predict about 80% of responders and 65% of non-responders, said J. John Mann, professor of psychiatry at Columbia and a co-author of the study.

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