Columbia University Medical Center
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell
The Study was Conducted by Researchers at Columbia University Medical Center
January 5, 2009

In the study, researchers used high-resolution functional magnetic resonance imaging to map brain regions in 240 elderly subjects. They found a correlation between elevated blood glucose levels and reduced cerebral blood volume, or blood flow, in the dentate gyrus, an indication of reduced metabolic activity and function in that region of the brain.

By manipulating blood sugar levels in mice and monkeys, researchers said, they tried to confirm a cause-and-effect relationship between the glucose spikes and the reduced blood volume, Dr. [Scott] Small said.

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