Study Name: Ketamine for Major Depression
Principal Investigator: J. John Mann, M.D.
Purpose of Study: To determine how ketamine, a new experimental treatment, works as an antidepressant by using MRI scanning (no radiation involved) during the actual ketamine treatment of 40 minutes and for a short time afterwards. When effective, ketamine generally works in as little as four hours.
Treatment Offered: One dose of ketamine followed by an oral medication called riluzole for 8 weeks to maintain benefit in those whose depression responds to ketamine
Eligibility: A diagnosis of major depression and a history of any kind treatment for depression at any point in the past.
Funding: The Brain and Behavior Foundation
Contact information: Shayna Friedman