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Fighting for Approval of Huntington's Disease Drug

October 28, 2008

Jonathan Monkemeyer, an engineer by training, worked long and hard on the heartfelt four-minute talk he presented at a packed Food and Drug Administration advisory committee meeting last December. But even without saying a word, Sheryl Monkemeyer was far more expressive than her husband could ever be. … Columbia University neurologist Nancy Wexler, who spearheaded the research leading to a genetic test for Huntington's, says she had hoped the FDA wouldn't need an advisory committee meeting ‘because the merits of this drug were so obvious.’ But, says Wexler, whose mother died of Huntington's, ‘I think there were a lot of misconceptions about how debilitating these incredibly engulfing, abnormal movements are.’

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