Columbia University Medical Center
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell
August 24, 2009

Pharmacists are allowed -- and in some states, mandated -- to swap a brand name drug for its generic counterpart, but concerns linger about whether some generics actually measure up. Although generic medications have long been touted for their cost-effectiveness, concerns have been raised about the effect of generic substitution in everyday practice, differences in bioequivalence standards for FDA approval, and recent manufacturing recalls. In this first of a three-part series examining these issues, MedPage Today looks at the problems that can arise when generics are substituted for brand name products -- or when switches are made between generic drugs from different manufacturers

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