Columbia University Medical Center
Ranked #1 in Psychiatry
U.S. News & World Report
Ranked #1 in Research Funding
National Institutes of Health
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell

Clinical Therapeutics

B. Timothy Walsh, MD, Chief


The Division of Clinical Therapeutics focuses on clinical research with adults suffering from non-psychotic psychiatric disorders, including anxiety, depression, OCD and related disorders like hoarding disorder, PTSD, eating disorders, gambling disorders, illness anxiety, and somatic symptom disorders.  Our goal is to transform outcomes for people with these disorders by discovering what causes them, studying which treatments work best for whom, and testing novel treatments, with the goal of identifying new targets for treatment development.

The division is comprised of six administrative units: Anxiety Disorders Clinic, Anxiety Genetics Unit, Clinical Psychobiology/Biological Studies Unit, Center for Neuroinflammatory Disorders and Biobehavioral Medicine/Lyme Disease, Depression Evaluation Service, and Eating Disorders Research Unit.

Our current studies include clinical trials using both medication and psychotherapy to investigate new treatments for depressive disorders, a range of anxiety disorders and eating disorders, OCD and Hoarding Disorder, PTSD, gambling disorders, hypochondriasis, neuropsychiatric symptoms following Lyme disease, and fatigue associated with HIV. We also use various techniques to uncover psychological, biological, genetic, and environmental factors that contribute to the development and persistence of these serious psychiatric problems. These include brain imagining, molecular genetics, immune challenge studies, and neuropsychological assessment. Finally, we partner with government and private clinical programs in the community to study how to implement the evidence-based treatments we have developed in diverse populations.

There is no charge to research participants volunteering for our treatment or biological studies.

Please visit our research clinic websites for more information.


Related Websites:

Eating Disorders Research Unit


Anxiety Disorders Clinic

     • Center for Obsessive-Compulsive Disorder and Related Disorders

     • Social Anxiety Disorder

     • Generalized Anxiety Disorder

     • Trauma and PTSD Program

     • Gambling Disorders Clinic

     • Hispanic Treatment Program

     • Hoarding Disorder Research Program

     • NYS Center of Excellence for Cultural Competence

     • Breast Cancer/Depression Study


Depression Evaluation Service


Lyme and Tick-Borne Diseases Research Center





hora interior