Jonathan Javitch, MD, PhD, Chief
Research in the Division of Molecular Therapeutics focuses on understanding molecular and cellular processes that underlie behavior, with an emphasis on existing or novel targets for therapeutic intervention in psychiatric disorders. The Division has a specialized expertise in dopaminergic signaling and the function of midbrain dopamine neurons. These neurons are thought to play an important role in the rewarding effects of abused drugs, as well as to figure importantly in the pathogenesis of schizophrenia. Projects are multidisciplinary and range from studies on the biochemical and biophysical characterization of basic molecular processes that underlie drug responses, to cellular physiology, and to behavior.