Faculty members of the Columbia Department of Psychiatry run a wide variety of Research Laboratories. Columbia Psychiatry faculty members are recognized as world leaders in the neurosciences and related disciplines, and have made major advances in understanding the biology of the mind. Research in these laboratories range from basic biological sciences to epidemiological, psychometric, neuroimaging and other areas. Many laboratories enroll people with psychiatric diagnoses and healthy controls to study psychiatric disorders using cutting edge technologies such as MRI and PET scanning.
Cloning of genes which predispose to neuropsychiatric illness is proceeding rapidly of late. Yet identifying such predisposition genes is but a first step in understanding the pathophysiology of mental illnesses.
Schizophrenia is a debilitating disease that is characterized by positive, negative, and cognitive symptoms. Understanding the cognitive symptoms in molecular terms is central for the study of schizophrenia.
We conduct studies aimed at assessing neurodevelopment of these circuits in adolescents with eating disorders (Bulimia Nervosa and Anorexia Nervosa) and in children, adolescents, and adults with Obsessive-Compulsive Disorder and Tourette’s Syndrome, as well as healthy individuals.